A molecular genetic linkage map of mouse chromosome 13 anchored by the beige ( bg ) and satin ( sa ) loci
Identifieur interne : 000A83 ( Main/Exploration ); précédent : 000A82; suivant : 000A84A molecular genetic linkage map of mouse chromosome 13 anchored by the beige ( bg ) and satin ( sa ) loci
Auteurs : Monica J. Justice [États-Unis] ; Colleen M. Silan [États-Unis] ; Jeffrey D. Ceci [États-Unis] ; Arthur M. Buchberg [États-Unis] ; Neal G. Copeland [États-Unis] ; Nancy A. Jenkins [États-Unis]Source :
- Genomics [ 0888-7543 ] ; 1990.
English descriptors
- Teeft :
- Allele, Anchor loci, Backcross, Backcrosses, Buchberg, Cancer research facility, Cdna, Cell genet, Chromosomal, Chromosome, Comparative mapping, Confidence limit, Crossover, Davisson, Dhfr, Distal region, Gene, Gene order, Genet, Hexb, Hilda, Hilda probe, Homolog, Homology, Homozygous mice, Human chromosome, Human chromosomes, Inbred, Inhba, Interspecific, Interspecific backcross, Interspecific backcross analysis, Interspecific backcross mice, Interspecific backcrosses, Laminin, Linkage, Linkage maps, Locus, Marker, Molecular markers, Mouse, Mouse chromosome, Mouse genome, Mouse mutations, Murine, Mutation, Phenotypic, Probe, Progeny, Proximal region, Receptor, Recombination, Recombination frequencies, Reductase, Rflps, Ribonucleotide reductase, Solum, Somatic cell hybrids, Spretus, Sscp, Subunit, Syntenic group, Tcrg, Total number, Unpublished results.
Abstract
Abstract: A molecular genetic linkage map of mouse chromosome 13 was constructed using cloned DNA markers and interspecific backcross mice from two independent crosses. The map locations of Ctla-3, Dhfr, Fim-1, 4 12, Hexb, Hilda, Inhba, Lamb-1.13, Ral, Rrm2-ps3, and Tcrg were determined with respect to the beige (bg) and satin (sa) loci. The map locations of these genes confirm and extend regions of homology between mouse chromosome 13 and human chromosomes 5 and 7, and identify a region of homology between mouse chromosome 13 and human chromosome 6. The molecular genetic linkage map of chromosome 13 provides a framework for establishing linkage relationships between cloned DNA markers and known mouse mutations and for identifying homologous genes in mice and humans that may be involved in disease processes.
Url:
DOI: 10.1016/0888-7543(90)90575-F
Affiliations:
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Le document en format XML
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<term>Anchor loci</term>
<term>Backcross</term>
<term>Backcrosses</term>
<term>Buchberg</term>
<term>Cancer research facility</term>
<term>Cdna</term>
<term>Cell genet</term>
<term>Chromosomal</term>
<term>Chromosome</term>
<term>Comparative mapping</term>
<term>Confidence limit</term>
<term>Crossover</term>
<term>Davisson</term>
<term>Dhfr</term>
<term>Distal region</term>
<term>Gene</term>
<term>Gene order</term>
<term>Genet</term>
<term>Hexb</term>
<term>Hilda</term>
<term>Hilda probe</term>
<term>Homolog</term>
<term>Homology</term>
<term>Homozygous mice</term>
<term>Human chromosome</term>
<term>Human chromosomes</term>
<term>Inbred</term>
<term>Inhba</term>
<term>Interspecific</term>
<term>Interspecific backcross</term>
<term>Interspecific backcross analysis</term>
<term>Interspecific backcross mice</term>
<term>Interspecific backcrosses</term>
<term>Laminin</term>
<term>Linkage</term>
<term>Linkage maps</term>
<term>Locus</term>
<term>Marker</term>
<term>Molecular markers</term>
<term>Mouse</term>
<term>Mouse chromosome</term>
<term>Mouse genome</term>
<term>Mouse mutations</term>
<term>Murine</term>
<term>Mutation</term>
<term>Phenotypic</term>
<term>Probe</term>
<term>Progeny</term>
<term>Proximal region</term>
<term>Receptor</term>
<term>Recombination</term>
<term>Recombination frequencies</term>
<term>Reductase</term>
<term>Rflps</term>
<term>Ribonucleotide reductase</term>
<term>Solum</term>
<term>Somatic cell hybrids</term>
<term>Spretus</term>
<term>Sscp</term>
<term>Subunit</term>
<term>Syntenic group</term>
<term>Tcrg</term>
<term>Total number</term>
<term>Unpublished results</term>
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<front><div type="abstract" xml:lang="en">Abstract: A molecular genetic linkage map of mouse chromosome 13 was constructed using cloned DNA markers and interspecific backcross mice from two independent crosses. The map locations of Ctla-3, Dhfr, Fim-1, 4 12, Hexb, Hilda, Inhba, Lamb-1.13, Ral, Rrm2-ps3, and Tcrg were determined with respect to the beige (bg) and satin (sa) loci. The map locations of these genes confirm and extend regions of homology between mouse chromosome 13 and human chromosomes 5 and 7, and identify a region of homology between mouse chromosome 13 and human chromosome 6. The molecular genetic linkage map of chromosome 13 provides a framework for establishing linkage relationships between cloned DNA markers and known mouse mutations and for identifying homologous genes in mice and humans that may be involved in disease processes.</div>
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<name sortKey="Buchberg, Arthur M" sort="Buchberg, Arthur M" uniqKey="Buchberg A" first="Arthur M." last="Buchberg">Arthur M. Buchberg</name>
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<name sortKey="Copeland, Neal G" sort="Copeland, Neal G" uniqKey="Copeland N" first="Neal G." last="Copeland">Neal G. Copeland</name>
<name sortKey="Jenkins, Nancy A" sort="Jenkins, Nancy A" uniqKey="Jenkins N" first="Nancy A." last="Jenkins">Nancy A. Jenkins</name>
<name sortKey="Silan, Colleen M" sort="Silan, Colleen M" uniqKey="Silan C" first="Colleen M." last="Silan">Colleen M. Silan</name>
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